Entity Details

Primary name ADRB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP18762
EntryNameADRB2_MOUSE
FullNameBeta-2 adrenergic receptor
TaxID10090
Evidenceevidence at protein level
Length418
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesAdrb2

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001965 G-protein alpha-subunit binding
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine
GO:0002024 diet induced thermogenesis
GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
GO:0002028 regulation of sodium ion transport
GO:0002032 desensitization of G protein-coupled receptor signaling pathway by arrestin
GO:0002086 diaphragm contraction
GO:0003059 positive regulation of the force of heart contraction by epinephrine
GO:0004930 G protein-coupled receptor activity
GO:0004941 beta2-adrenergic receptor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0006898 receptor-mediated endocytosis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0008179 adenylate cyclase binding
GO:0008284 positive regulation of cell population proliferation
GO:0008306 associative learning
GO:0009409 response to cold
GO:0010739 positive regulation of protein kinase A signaling
GO:0010765 positive regulation of sodium ion transport
GO:0015459 potassium channel regulator activity
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0016525 negative regulation of angiogenesis
GO:0019899 enzyme binding
GO:0030279 negative regulation of ossification
GO:0030424 axon
GO:0030425 dendrite
GO:0030501 positive regulation of bone mineralization
GO:0031649 heat generation
GO:0031713 B2 bradykinin receptor binding
GO:0032781 positive regulation of ATPase activity
GO:0032809 neuronal cell body membrane
GO:0035249 synaptic transmission, glutamatergic
GO:0035255 ionotropic glutamate receptor binding
GO:0035811 negative regulation of urine volume
GO:0040015 negative regulation of multicellular organism growth
GO:0042060 wound healing
GO:0042383 sarcolemma
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043197 dendritic spine
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043268 positive regulation of potassium ion transport
GO:0043410 positive regulation of MAPK cascade
GO:0044877 protein-containing complex binding
GO:0045453 bone resorption
GO:0045823 positive regulation of heart contraction
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045986 negative regulation of smooth muscle contraction
GO:0048633 positive regulation of skeletal muscle tissue growth
GO:0050728 negative regulation of inflammatory response
GO:0050873 brown fat cell differentiation
GO:0051380 norepinephrine binding
GO:0051721 protein phosphatase 2A binding
GO:0051924 regulation of calcium ion transport
GO:0051930 regulation of sensory perception of pain
GO:0060079 excitatory postsynaptic potential
GO:0061885 positive regulation of mini excitatory postsynaptic potential
GO:0071456 cellular response to hypoxia
GO:0071875 adrenergic receptor signaling pathway
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0090331 negative regulation of platelet aggregation
GO:0090722 receptor-receptor interaction
GO:0098978 glutamatergic synapse
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1901098 positive regulation of autophagosome maturation
GO:1904504 positive regulation of lipophagy
GO:1904646 cellular response to amyloid-beta
GO:1905665 positive regulation of calcium ion import across plasma membrane
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2000969 positive regulation of AMPA receptor activity

Subcellular Location

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Subcellular Location
Cell membrane
Early endosome
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000332 Beta 2 adrenoceptorFamilyFamily
IPR002233 Adrenoceptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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