Entity Details

Primary name IL10_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP18893
EntryNameIL10_MOUSE
FullNameInterleukin-10
TaxID10090
Evidenceevidence at protein level
Length178
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesIl10

GO terms

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GOName
GO:0001818 negative regulation of cytokine production
GO:0001819 positive regulation of cytokine production
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002237 response to molecule of bacterial origin
GO:0002639 positive regulation of immunoglobulin production
GO:0002719 negative regulation of cytokine production involved in immune response
GO:0002875 negative regulation of chronic inflammatory response to antigenic stimulus
GO:0002904 positive regulation of B cell apoptotic process
GO:0005125 cytokine activity
GO:0005141 interleukin-10 receptor binding
GO:0005615 extracellular space
GO:0006955 immune response
GO:0007568 aging
GO:0008285 negative regulation of cell population proliferation
GO:0010468 regulation of gene expression
GO:0010507 negative regulation of autophagy
GO:0014823 response to activity
GO:0014854 response to inactivity
GO:0030886 negative regulation of myeloid dendritic cell activation
GO:0030889 negative regulation of B cell proliferation
GO:0032689 negative regulation of interferon-gamma production
GO:0032695 negative regulation of interleukin-12 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032868 response to insulin
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0034465 response to carbon monoxide
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0042493 response to drug
GO:0042742 defense response to bacterium
GO:0042832 defense response to protozoan
GO:0043032 positive regulation of macrophage activation
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045347 negative regulation of MHC class II biosynthetic process
GO:0045348 positive regulation of MHC class II biosynthetic process
GO:0045787 positive regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046983 protein dimerization activity
GO:0050728 negative regulation of inflammatory response
GO:0050807 regulation of synapse organization
GO:0051045 negative regulation of membrane protein ectodomain proteolysis
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051384 response to glucocorticoid
GO:0051930 regulation of sensory perception of pain
GO:0060302 negative regulation of cytokine activity
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0071222 cellular response to lipopolysaccharide
GO:0071392 cellular response to estradiol stimulus
GO:0097421 liver regeneration
GO:1900100 positive regulation of plasma cell differentiation
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1903034 regulation of response to wounding
GO:1903208 negative regulation of hydrogen peroxide-induced neuron death
GO:1903672 positive regulation of sprouting angiogenesis
GO:1904057 negative regulation of sensory perception of pain
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:2000273 positive regulation of signaling receptor activity
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000098 Interleukin-10FamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR020423 Interleukin-10, conserved siteSiteConserved site
IPR020443 Interleukin-10/19/20/22/24/26 familyFamilyFamily

Diseases

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Interactions

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