Entity Details

Primary name KALRN_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2CG49
EntryNameKALRN_MOUSE
FullNameKalirin
TaxID10090
Evidenceevidence at protein level
Length2964
SequenceStatuscomplete
DateCreated2007-10-23
DateModified2021-06-02

Ontological Relatives

GenesKalrn

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0007399 nervous system development
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0007417 central nervous system development
GO:0007528 neuromuscular junction development
GO:0007595 lactation
GO:0007613 memory
GO:0008344 adult locomotory behavior
GO:0014069 postsynaptic density
GO:0019899 enzyme binding
GO:0035176 social behavior
GO:0035556 intracellular signal transduction
GO:0042711 maternal behavior
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043547 positive regulation of GTPase activity
GO:0046872 metal ion binding
GO:0046959 habituation
GO:0048471 perinuclear region of cytoplasm
GO:0050773 regulation of dendrite development
GO:0060125 negative regulation of growth hormone secretion
GO:0060137 maternal process involved in parturition
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
GO:0098793 presynapse
GO:0098885 modification of postsynaptic actin cytoskeleton
GO:0098978 glutamatergic synapse
GO:0098989 NMDA selective glutamate receptor signaling pathway
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1905274 regulation of modification of postsynaptic actin cytoskeleton

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR001251 CRAL-TRIO lipid binding domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR028570 Rho GDP/GTP exchange factor Kalirin/TRIOFamilyFamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036865 CRAL-TRIO lipid binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
KALRN_MOUSESNCAP_MOUSEBioGRID, IntAct23284848 details
KALRN_MOUSEHAP1_HUMANUniProt18192679 details