Entity Details

Primary name CYBR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ53TN4
EntryNameCYBR1_HUMAN
FullNamePlasma membrane ascorbate-dependent reductase CYBRD1
TaxID9606
Evidenceevidence at protein level
Length286
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesCYBRD1

GO terms

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GOName
GO:0000293 ferric-chelate reductase activity
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0006879 cellular iron ion homeostasis
GO:0010039 response to iron ion
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016491 oxidoreductase activity
GO:0016722 oxidoreductase activity, acting on metal ions
GO:0031526 brush border membrane
GO:0033215 reductive iron assimilation
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0055072 iron ion homeostasis
GO:0070062 extracellular exosome
GO:0140571 transmembrane ascorbate ferrireductase activity
GO:0140575 transmembrane monodehydroascorbate reductase activity
GO:0140576 ascorbate homeostasis

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR006593 Cytochrome b561/ferric reductase transmembraneDomainDomain
IPR028838 Plasma membrane ascorbate-dependent reductase CYBRD1FamilyFamily
IPR043205 Cytochrome b561/Cytochrome b reductase 1-likeFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB13257 Ferrous sulfate anhydrousDrugbanksmall molecule
DB14520 Tetraferric tricitrate decahydrateDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink