Entity Details

Primary name NELFE_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP19426
EntryNameNELFE_MOUSE
FullNameNegative elongation factor E
TaxID10090
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesNelfe

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0016604 nuclear body
GO:0032021 NELF complex
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1900364 negative regulation of mRNA polyadenylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR033102 Negative elongation factor EFamilyFamily
IPR034637 Negative elongation factor E, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NELFE_MOUSEHS90B_MOUSEIntAct22579285 details