Entity Details

Primary name BIP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP20029
EntryNameBIP_MOUSE
FullNameEndoplasmic reticulum chaperone BiP
TaxID10090
Evidenceevidence at protein level
Length655
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesHspa5

GO terms

Show/Hide Table
GOName
GO:0001554 luteolysis
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005790 smooth endoplasmic reticulum
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006983 ER overload response
GO:0008180 COP9 signalosome
GO:0009986 cell surface
GO:0010976 positive regulation of neuron projection development
GO:0016020 membrane
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0021589 cerebellum structural organization
GO:0021680 cerebellar Purkinje cell layer development
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030182 neuron differentiation
GO:0030335 positive regulation of cell migration
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030496 midbody
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0031072 heat shock protein binding
GO:0031204 posttranslational protein targeting to membrane, translocation
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031398 positive regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0034620 cellular response to unfolded protein
GO:0034663 endoplasmic reticulum chaperone complex
GO:0034976 response to endoplasmic reticulum stress
GO:0035437 maintenance of protein localization in endoplasmic reticulum
GO:0035690 cellular response to drug
GO:0040019 positive regulation of embryonic development
GO:0042026 protein refolding
GO:0042149 cellular response to glucose starvation
GO:0042220 response to cocaine
GO:0043022 ribosome binding
GO:0043066 negative regulation of apoptotic process
GO:0043209 myelin sheath
GO:0043231 intracellular membrane-bounded organelle
GO:0044183 protein folding chaperone
GO:0051082 unfolded protein binding
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051402 neuron apoptotic process
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0051787 misfolded protein binding
GO:0071236 cellular response to antibiotic
GO:0071277 cellular response to calcium ion
GO:0071287 cellular response to manganese ion
GO:0071320 cellular response to cAMP
GO:0071353 cellular response to interleukin-4
GO:0071480 cellular response to gamma radiation
GO:0097501 stress response to metal ion
GO:1901998 toxin transport
GO:1903895 negative regulation of IRE1-mediated unfolded protein response
GO:1904313 response to methamphetamine hydrochloride
GO:1990090 cellular response to nerve growth factor stimulus

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Endoplasmic reticulum lumen

Domains

Show/Hide Table
DomainNameCategoryType
IPR013126 Heat shock protein 70 familyFamilyFamily
IPR018181 Heat shock protein 70, conserved siteSiteConserved site
IPR029047 Heat shock protein 70kD, peptide-binding domain superfamilyFamilyHomologous superfamily
IPR029048 Heat shock protein 70kD, C-terminal domain superfamilyFamilyHomologous superfamily
IPR042050 Endoplasmic reticulum chaperone BIP, nucleotide-binding domainDomainDomain
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

Show/Hide Table