Entity Details

Primary name TBXT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP20293
EntryNameTBXT_MOUSE
FullNameT-box transcription factor T
TaxID10090
Evidenceevidence at protein level
Length436
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesT

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001570 vasculogenesis
GO:0001707 mesoderm formation
GO:0001708 cell fate specification
GO:0001756 somitogenesis
GO:0001839 neural plate morphogenesis
GO:0001843 neural tube closure
GO:0003007 heart morphogenesis
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007341 penetration of zona pellucida
GO:0007498 mesoderm development
GO:0007509 mesoderm migration involved in gastrulation
GO:0008284 positive regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0009952 anterior/posterior pattern specification
GO:0014028 notochord formation
GO:0022414 reproductive process
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030903 notochord development
GO:0036342 post-anal tail morphogenesis
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048706 embryonic skeletal system development
GO:0055007 cardiac muscle cell differentiation
GO:0060349 bone morphogenesis
GO:0060395 SMAD protein signal transduction
GO:0061371 determination of heart left/right asymmetry
GO:0071300 cellular response to retinoic acid
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR002070 Transcription factor, BrachyuryFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions