Entity Details

Primary name BDNF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP21237
EntryNameBDNF_MOUSE
FullNameBrain-derived neurotrophic factor
TaxID10090
Evidenceevidence at protein level
Length249
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesBdnf

GO terms

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GOName
GO:0001657 ureteric bud development
GO:0001662 behavioral fear response
GO:0005163 nerve growth factor receptor binding
GO:0005169 neurotrophin TRKB receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005788 endoplasmic reticulum lumen
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007399 nervous system development
GO:0007406 negative regulation of neuroblast proliferation
GO:0007411 axon guidance
GO:0007412 axon target recognition
GO:0007416 synapse assembly
GO:0007422 peripheral nervous system development
GO:0007611 learning or memory
GO:0007612 learning
GO:0007613 memory
GO:0007623 circadian rhythm
GO:0007631 feeding behavior
GO:0008021 synaptic vesicle
GO:0008038 neuron recognition
GO:0008083 growth factor activity
GO:0010832 negative regulation of myotube differentiation
GO:0010976 positive regulation of neuron projection development
GO:0014047 glutamate secretion
GO:0016358 dendrite development
GO:0016607 nuclear speck
GO:0019222 regulation of metabolic process
GO:0021675 nerve development
GO:0030061 mitochondrial crista
GO:0030141 secretory granule
GO:0030424 axon
GO:0030425 dendrite
GO:0030516 regulation of axon extension
GO:0031099 regeneration
GO:0031410 cytoplasmic vesicle
GO:0032229 negative regulation of synaptic transmission, GABAergic
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0038180 nerve growth factor signaling pathway
GO:0042490 mechanoreceptor differentiation
GO:0042493 response to drug
GO:0042596 fear response
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043195 terminal bouton
GO:0043204 perikaryon
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045843 negative regulation of striated muscle tissue development
GO:0046668 regulation of retinal cell programmed cell death
GO:0048148 behavioral response to cocaine
GO:0048167 regulation of synaptic plasticity
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0048172 regulation of short-term neuronal synaptic plasticity
GO:0048471 perinuclear region of cytoplasm
GO:0048668 collateral sprouting
GO:0048670 regulation of collateral sprouting
GO:0048672 positive regulation of collateral sprouting
GO:0048675 axon extension
GO:0048812 neuron projection morphogenesis
GO:0048839 inner ear development
GO:0050804 modulation of chemical synaptic transmission
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051965 positive regulation of synapse assembly
GO:0060079 excitatory postsynaptic potential
GO:0060080 inhibitory postsynaptic potential
GO:0060548 negative regulation of cell death
GO:0061193 taste bud development
GO:0097484 dendrite extension
GO:0098794 postsynapse
GO:0099083 retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission
GO:1900122 positive regulation of receptor binding
GO:1901215 negative regulation of neuron death
GO:1990138 neuron projection extension
GO:2000324 positive regulation of glucocorticoid receptor signaling pathway
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002072 Nerve growth factor-relatedDomainDomain
IPR019846 Nerve growth factor conserved siteSiteConserved site
IPR020408 Nerve growth factor-likeFamilyFamily
IPR020430 Brain-derived neurotrophic factorFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

3 interactions