Entity Details

Primary name TAP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP21958
EntryNameTAP1_MOUSE
FullNameAntigen peptide transporter 1
TaxID10090
Evidenceevidence at protein level
Length724
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesTap1

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0002250 adaptive immune response
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0006952 defense response
GO:0015031 protein transport
GO:0015433 ABC-type peptide antigen transporter activity
GO:0015440 ABC-type peptide transporter activity
GO:0015833 peptide transport
GO:0016021 integral component of membrane
GO:0016887 ATP hydrolysis activity
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 MHC class Ib protein binding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030670 phagocytic vesicle membrane
GO:0034451 centriolar satellite
GO:0042270 protection from natural killer cell mediated cytotoxicity
GO:0042288 MHC class I protein binding
GO:0042605 peptide antigen binding
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042803 protein homodimerization activity
GO:0042824 MHC class I peptide loading complex
GO:0042825 TAP complex
GO:0043231 intracellular membrane-bounded organelle
GO:0043531 ADP binding
GO:0044877 protein-containing complex binding
GO:0046872 metal ion binding
GO:0046967 cytosol to endoplasmic reticulum transport
GO:0046978 TAP1 binding
GO:0046979 TAP2 binding
GO:0046980 tapasin binding
GO:0055085 transmembrane transport
GO:1904680 peptide transmembrane transporter activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR013305 ABC transporter Tap-likeFamilyFamily
IPR013306 Antigen peptide transporter 1FamilyFamily
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily
IPR039421 Type 1 protein exporterFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TAP1_MOUSEB2MG_MOUSEBioGRID19366690 details
TAP1_MOUSETPSN_MOUSEBioGRID9973410 details