Entity Details

Primary name HEMH_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP22315
EntryNameHEMH_MOUSE
FullNameFerrochelatase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length420
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0004325 ferrochelatase activity
GO:0005506 iron ion binding
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0006783 heme biosynthetic process
GO:0008203 cholesterol metabolic process
GO:0009416 response to light stimulus
GO:0009589 detection of UV
GO:0010468 regulation of gene expression
GO:0010999 regulation of eIF2 alpha phosphorylation by heme
GO:0020037 heme binding
GO:0030218 erythrocyte differentiation
GO:0030350 iron-responsive element binding
GO:0034379 very-low-density lipoprotein particle assembly
GO:0046501 protoporphyrinogen IX metabolic process
GO:0046906 tetrapyrrole binding
GO:0046984 regulation of hemoglobin biosynthetic process
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0055072 iron ion homeostasis

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001015 FerrochelataseFamilyFamily
IPR019772 Ferrochelatase, active siteSiteActive site
IPR033644 Ferrochelatase, C-terminalDomainDomain
IPR033659 Ferrochelatase, N-terminalDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HEMH_MOUSEPGRC2_HUMANIntAct27599036 details