Entity Details

Primary name PGH1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP22437
EntryNamePGH1_MOUSE
FullNameProstaglandin G/H synthase 1
TaxID10090
Evidenceevidence at protein level
Length602
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesPtgs1

GO terms

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GOName
GO:0001516 prostaglandin biosynthetic process
GO:0001750 photoreceptor outer segment
GO:0004601 peroxidase activity
GO:0004666 prostaglandin-endoperoxide synthase activity
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0006693 prostaglandin metabolic process
GO:0006954 inflammatory response
GO:0006979 response to oxidative stress
GO:0007612 learning
GO:0007613 memory
GO:0008217 regulation of blood pressure
GO:0010700 negative regulation of norepinephrine secretion
GO:0019233 sensory perception of pain
GO:0019371 cyclooxygenase pathway
GO:0020037 heme binding
GO:0030216 keratinocyte differentiation
GO:0032811 negative regulation of epinephrine secretion
GO:0035633 maintenance of blood-brain barrier
GO:0042127 regulation of cell population proliferation
GO:0043231 intracellular membrane-bounded organelle
GO:0045907 positive regulation of vasoconstriction
GO:0045987 positive regulation of smooth muscle contraction
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR010255 Haem peroxidase superfamilyFamilyHomologous superfamily
IPR019791 Haem peroxidase, animal-typeFamilyFamily
IPR029580 Prostaglandin G/H synthase 1FamilyFamily
IPR037120 Haem peroxidase domain superfamily, animal typeFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PGH1_MOUSENUCB1_MOUSEBioGRID8643612 details