Entity Details

Primary name RARB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP22605
EntryNameRARB_MOUSE
FullNameRetinoic acid receptor beta
TaxID10090
Evidenceevidence at protein level
Length482
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesRarb

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001657 ureteric bud development
GO:0002068 glandular epithelial cell development
GO:0003148 outflow tract septum morphogenesis
GO:0003406 retinal pigment epithelium development
GO:0003417 growth plate cartilage development
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009755 hormone-mediated signaling pathway
GO:0021756 striatum development
GO:0022008 neurogenesis
GO:0030154 cell differentiation
GO:0031641 regulation of myelination
GO:0032331 negative regulation of chondrocyte differentiation
GO:0035116 embryonic hindlimb morphogenesis
GO:0035264 multicellular organism growth
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043068 positive regulation of programmed cell death
GO:0043565 sequence-specific DNA binding
GO:0044877 protein-containing complex binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0048048 embryonic eye morphogenesis
GO:0048384 retinoic acid receptor signaling pathway
GO:0048566 embryonic digestive tract development
GO:0055012 ventricular cardiac muscle cell differentiation
GO:0060041 retina development in camera-type eye
GO:0060348 bone development
GO:0061037 negative regulation of cartilage development
GO:0061351 neural precursor cell proliferation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR003078 Retinoic acid receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
RARB_MOUSEING4_MOUSEBioGRID, IntAct, MINT20211142 31420607 details
RARB_MOUSEASXL1_MOUSEUniProt16606617 details
RARB_MOUSEEP300_MOUSEBioGRID21722948 details