Entity Details

Primary name CD3E_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP22646
EntryNameCD3E_MOUSE
FullNameT-cell surface glycoprotein CD3 epsilon chain
TaxID10090
Evidenceevidence at protein level
Length189
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesCd3e

GO terms

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GOName
GO:0001772 immunological synapse
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002250 adaptive immune response
GO:0002669 positive regulation of T cell anergy
GO:0004888 transmembrane signaling receptor activity
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0007166 cell surface receptor signaling pathway
GO:0007584 response to nutrient
GO:0009897 external side of plasma membrane
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0016358 dendrite development
GO:0017124 SH3 domain binding
GO:0021549 cerebellum development
GO:0031295 T cell costimulation
GO:0032729 positive regulation of interferon-gamma production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0042101 T cell receptor complex
GO:0042102 positive regulation of T cell proliferation
GO:0042105 alpha-beta T cell receptor complex
GO:0042802 identical protein binding
GO:0043197 dendritic spine
GO:0044297 cell body
GO:0045059 positive thymic T cell selection
GO:0045060 negative thymic T cell selection
GO:0045879 negative regulation of smoothened signaling pathway
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0046649 lymphocyte activation
GO:0046982 protein heterodimerization activity
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 positive regulation of calcium-mediated signaling
GO:0050852 T cell receptor signaling pathway
GO:0050870 positive regulation of T cell activation
GO:0097190 apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003110 Phosphorylated immunoreceptor signalling ITAMRepeatRepeat
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015484 CD3 protein, epsilon/gamma/delta subunitFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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