Entity Details

Primary name TTP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP22893
EntryNameTTP_MOUSE
FullNamemRNA decay activator protein ZFP36
TaxID10090
Evidenceevidence at protein level
Length319
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesZfp36

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 P-body
GO:0003677 DNA binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006402 mRNA catabolic process
GO:0007275 multicellular organism development
GO:0009611 response to wounding
GO:0010494 cytoplasmic stress granule
GO:0010837 regulation of keratinocyte proliferation
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019957 C-C chemokine binding
GO:0031072 heat shock protein binding
GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay
GO:0032680 regulation of tumor necrosis factor production
GO:0032703 negative regulation of interleukin-2 production
GO:0032897 negative regulation of viral transcription
GO:0035278 miRNA mediated inhibition of translation
GO:0035556 intracellular signal transduction
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0038066 p38MAPK cascade
GO:0042594 response to starvation
GO:0043488 regulation of mRNA stability
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0044877 protein-containing complex binding
GO:0045600 positive regulation of fat cell differentiation
GO:0045616 regulation of keratinocyte differentiation
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045647 negative regulation of erythrocyte differentiation
GO:0046872 metal ion binding
GO:0050728 negative regulation of inflammatory response
GO:0050779 RNA destabilization
GO:0051028 mRNA transport
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0061014 positive regulation of mRNA catabolic process
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0070063 RNA polymerase binding
GO:0070935 3'-UTR-mediated mRNA stabilization
GO:0071222 cellular response to lipopolysaccharide
GO:0071356 cellular response to tumor necrosis factor
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071889 14-3-3 protein binding
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:1901835 positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA
GO:1902172 regulation of keratinocyte apoptotic process
GO:1904246 negative regulation of polynucleotide adenylyltransferase activity
GO:1904582 positive regulation of intracellular mRNA localization
GO:1990904 ribonucleoprotein complex
GO:2000637 positive regulation of gene silencing by miRNA

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic granule
Nucleus

Domains

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DomainNameCategoryType
IPR000571 Zinc finger, CCCH-typeDomainDomain
IPR036855 Zinc finger, CCCH-type superfamilyFamilyHomologous superfamily

Diseases

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