Entity Details

Primary name HEM3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP22907
EntryNameHEM3_MOUSE
FullNamePorphobilinogen deaminase
TaxID10090
Evidenceevidence at protein level
Length361
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesHmbs

GO terms

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GOName
GO:0001889 liver development
GO:0004418 hydroxymethylbilane synthase activity
GO:0004852 uroporphyrinogen-III synthase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006778 porphyrin-containing compound metabolic process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006783 heme biosynthetic process
GO:0018160 peptidyl-pyrromethane cofactor linkage
GO:0030424 axon
GO:0031406 carboxylic acid binding
GO:0033014 tetrapyrrole biosynthetic process
GO:0042493 response to drug
GO:0043176 amine binding
GO:0048471 perinuclear region of cytoplasm

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000860 Porphobilinogen deaminaseFamilyFamily
IPR022417 Porphobilinogen deaminase, N-terminalDomainDomain
IPR022418 Porphobilinogen deaminase, C-terminalDomainDomain
IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding siteSiteBinding site
IPR036803 Porphobilinogen deaminase, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HEM3_MOUSERANB9_MOUSEBioGRID12917623 details