Entity Details

Primary name KPCL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP23298
EntryNameKPCL_MOUSE
FullNameProtein kinase C eta type
TaxID10090
Evidenceevidence at protein level
Length683
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesPrkch

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0004699 calcium-independent protein kinase C activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0016020 membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0019899 enzyme binding
GO:0031267 small GTPase binding
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035556 intracellular signal transduction
GO:0045618 positive regulation of keratinocyte differentiation
GO:0046872 metal ion binding
GO:0050861 positive regulation of B cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060252 positive regulation of glial cell proliferation
GO:0070528 protein kinase C signaling
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR014376 Protein kinase C, delta/epsilon/eta/theta typesFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain
IPR027431 Protein kinase C, etaFamilyFamily
IPR034665 Novel protein kinase C eta, catalytic domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
KPCL_MOUSEMTR1A_HUMANBioGRID, IntAct26514267 details