Entity Details

Primary name NHLC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6VVB1
EntryNameNHLC1_HUMAN
FullNameE3 ubiquitin-protein ligase NHLRC1
TaxID9606
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesNHLRC1

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005978 glycogen biosynthetic process
GO:0006914 autophagy
GO:0010468 regulation of gene expression
GO:0031398 positive regulation of protein ubiquitination
GO:0034976 response to endoplasmic reticulum stress
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045859 regulation of protein kinase activity
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0061630 ubiquitin protein ligase activity
GO:1903076 regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR011042 Six-bladed beta-propeller, TolB-likeFamilyHomologous superfamily
IPR013017 NHL repeat, subgroupRepeatRepeat
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NHLC1_HUMANEPM2A_MOUSEMINT22578008 details