Entity Details

Primary name 5HT3A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP23979
EntryName5HT3A_MOUSE
FullName5-hydroxytryptamine receptor 3A
TaxID10090
Evidenceevidence at protein level
Length487
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesHtr3a

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0022850 serotonin-gated cation-selective channel activity
GO:0030424 axon
GO:0030594 neurotransmitter receptor activity
GO:0032154 cleavage furrow
GO:0032414 positive regulation of ion transmembrane transporter activity
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0050877 nervous system process
GO:0051378 serotonin binding
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1904602 serotonin-activated cation-selective channel complex

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR008132 5-hydroxytryptamine 3 receptorFamilyFamily
IPR008133 5-hydroxytryptamine 3 receptor, A subunitFamilyFamily
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
5HT3A_MOUSE5HT3A_MOUSEDIP20023641 25119048 26724993 30401839 details