Entity Details

Primary name LKHA4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP24527
EntryNameLKHA4_MOUSE
FullNameLeukotriene A-4 hydrolase
TaxID10090
Evidenceevidence at protein level
Length611
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesLta4h

GO terms

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GOName
GO:0004177 aminopeptidase activity
GO:0004301 epoxide hydrolase activity
GO:0004463 leukotriene-A4 hydrolase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006691 leukotriene metabolic process
GO:0008270 zinc ion binding
GO:0019370 leukotriene biosynthetic process
GO:0043171 peptide catabolic process
GO:0044267 cellular protein metabolic process
GO:0045148 tripeptide aminopeptidase activity
GO:0070006 metalloaminopeptidase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolaseFamilyFamily
IPR012777 Leukotriene A4 hydrolase/leucine aminopeptidaseFamilyFamily
IPR014782 Peptidase M1, membrane alanine aminopeptidaseDomainDomain
IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminalDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR027268 Peptidase M4/M1, CTD superfamilyFamilyHomologous superfamily
IPR034015 Aminopeptidase, leukotriene A4 hydrolase-likeFamilyFamily
IPR038502 Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR042097 Aminopeptidase N-like , N-terminalFamilyHomologous superfamily

Diseases

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Interactions

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