Entity Details

Primary name IMDH2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP24547
EntryNameIMDH2_MOUSE
FullNameInosine-5'-monophosphate dehydrogenase 2
TaxID10090
Evidenceevidence at protein level
Length514
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesImpdh2

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003938 IMP dehydrogenase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006164 purine nucleotide biosynthetic process
GO:0006177 GMP biosynthetic process
GO:0006183 GTP biosynthetic process
GO:0007623 circadian rhythm
GO:0042802 identical protein binding
GO:0046651 lymphocyte proliferation
GO:0046872 metal ion binding
GO:0060041 retina development in camera-type eye
GO:0071353 cellular response to interleukin-4

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000644 CBS domainDomainDomain
IPR001093 IMP dehydrogenase/GMP reductaseDomainDomain
IPR005990 Inosine-5'-monophosphate dehydrogenaseFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR015875 IMP dehydrogenase / GMP reductase, conserved siteSiteConserved site

Diseases

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Interactions

3 interactions