Entity Details

Primary name PAX3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP24610
EntryNamePAX3_MOUSE
FullNamePaired box protein Pax-3
TaxID10090
Evidenceevidence at protein level
Length479
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesPax3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001755 neural crest cell migration
GO:0001843 neural tube closure
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0014807 regulation of somitogenesis
GO:0016477 cell migration
GO:0021527 spinal cord association neuron differentiation
GO:0021915 neural tube development
GO:0035914 skeletal muscle cell differentiation
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048066 developmental pigmentation
GO:0048663 neuron fate commitment
GO:0048856 anatomical structure development
GO:0055007 cardiac muscle cell differentiation
GO:0060538 skeletal muscle organ development
GO:0060594 mammary gland specification
GO:0071837 HMG box domain binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001523 Paired domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR022106 Paired box protein 7, C-terminalDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR043182 Paired DNA-binding domainDomainDomain
IPR043565 PAX familyFamilyFamily

Diseases

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