Entity Details

Primary name CRYAA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP24622
EntryNameCRYAA_MOUSE
FullNameAlpha-crystallin A chain
TaxID10090
Evidenceevidence at transcript level
Length196
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCryaa

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001934 positive regulation of protein phosphorylation
GO:0002088 lens development in camera-type eye
GO:0002089 lens morphogenesis in camera-type eye
GO:0005198 structural molecule activity
GO:0005212 structural constituent of eye lens
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006457 protein folding
GO:0006915 apoptotic process
GO:0007005 mitochondrion organization
GO:0007015 actin filament organization
GO:0007017 microtubule-based process
GO:0007021 tubulin complex assembly
GO:0010629 negative regulation of gene expression
GO:0030307 positive regulation of cell growth
GO:0032991 protein-containing complex
GO:0042542 response to hydrogen peroxide
GO:0042802 identical protein binding
GO:0043010 camera-type eye development
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046872 metal ion binding
GO:0048596 embryonic camera-type eye morphogenesis
GO:0051082 unfolded protein binding
GO:0060561 apoptotic process involved in morphogenesis
GO:0070141 response to UV-A
GO:0070309 lens fiber cell morphogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001436 Alpha crystallin/Small heat shock protein, animal typeFamilyFamily
IPR002068 Alpha crystallin/Hsp20 domainDomainDomain
IPR003090 Alpha-crystallin, N-terminalDomainDomain
IPR008978 HSP20-like chaperoneFamilyHomologous superfamily
IPR012274 Alpha-crystallin, subunit AFamilyFamily

Diseases

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Interactions

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