Entity Details

Primary name TBA1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ71U36
EntryNameTBA1A_HUMAN
FullNameTubulin alpha-1A chain
TaxID9606
Evidenceevidence at protein level
Length451
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesTUBA1A

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0007017 microtubule-based process
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0015630 microtubule cytoskeleton
GO:0019904 protein domain specific binding
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0031594 neuromuscular junction
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042802 identical protein binding
GO:0043209 myelin sheath
GO:0045121 membrane raft
GO:0050807 regulation of synapse organization
GO:0051301 cell division
GO:0055037 recycling endosome
GO:0070062 extracellular exosome
GO:0097711 ciliary basal body-plasma membrane docking

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000217 TubulinFamilyFamily
IPR002452 Alpha tubulinFamilyFamily
IPR003008 Tubulin/FtsZ, GTPase domainDomainDomain
IPR008280 Tubulin/FtsZ, C-terminalFamilyHomologous superfamily
IPR017975 Tubulin, conserved siteSiteConserved site
IPR018316 Tubulin/FtsZ, 2-layer sandwich domainDomainDomain
IPR023123 Tubulin, C-terminalFamilyHomologous superfamily
IPR036525 Tubulin/FtsZ, GTPase domain superfamilyFamilyHomologous superfamily
IPR037103 Tubulin/FtsZ-like, C-terminal domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00518 AlbendazoleDrugbanksmall molecule
DB00570 VinblastineDrugbanksmall molecule
DB00643 MebendazoleDrugbanksmall molecule
DB01873 Epothilone DDrugbanksmall molecule
DB03010 PatupiloneDrugbanksmall molecule
DB05147 CYT997Drugbanksmall molecule
DB07574 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDEDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule
DB15534 ColchiceineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TBA1A_HUMANPSA2_MOUSEBioGRID17139257 details