Entity Details

Primary name IL1RA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP25085
EntryNameIL1RA_MOUSE
FullNameInterleukin-1 receptor antagonist protein
TaxID10090
Evidenceevidence at transcript level
Length178
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesIl1rn

GO terms

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GOName
GO:0001660 fever generation
GO:0002437 inflammatory response to antigenic stimulus
GO:0005125 cytokine activity
GO:0005149 interleukin-1 receptor binding
GO:0005150 interleukin-1, type I receptor binding
GO:0005151 interleukin-1, type II receptor binding
GO:0005152 interleukin-1 receptor antagonist activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006629 lipid metabolic process
GO:0006953 acute-phase response
GO:0006954 inflammatory response
GO:0007613 memory
GO:0014050 negative regulation of glutamate secretion
GO:0019233 sensory perception of pain
GO:0030073 insulin secretion
GO:0030336 negative regulation of cell migration
GO:0031982 vesicle
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0043066 negative regulation of apoptotic process
GO:0043507 positive regulation of JUN kinase activity
GO:0045352 interleukin-1 type I receptor antagonist activity
GO:0045353 interleukin-1 type II receptor antagonist activity
GO:0045837 negative regulation of membrane potential
GO:0051384 response to glucocorticoid
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR000975 Interleukin-1 familyFamilyFamily
IPR003297 Interleukin-1 receptor antagonist/Interleukin-36FamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR020877 Interleukin-1 conserved siteSiteConserved site
IPR039348 Interleukin-1 receptor antagonistFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink