Entity Details

Primary name TNR1B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP25119
EntryNameTNR1B_MOUSE
FullNameTumor necrosis factor receptor superfamily member 1B
TaxID10090
Evidenceevidence at transcript level
Length474
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesTnfrsf1b

GO terms

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GOName
GO:0002718 regulation of cytokine production involved in immune response
GO:0002724 regulation of T cell cytokine production
GO:0003176 aortic valve development
GO:0003177 pulmonary valve development
GO:0003332 negative regulation of extracellular matrix constituent secretion
GO:0005031 tumor necrosis factor-activated receptor activity
GO:0005634 nucleus
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0007568 aging
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010614 negative regulation of cardiac muscle hypertrophy
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0031625 ubiquitin protein ligase binding
GO:0031641 regulation of myelination
GO:0031643 positive regulation of myelination
GO:0042129 regulation of T cell proliferation
GO:0043025 neuronal cell body
GO:0043120 tumor necrosis factor binding
GO:0043196 varicosity
GO:0045121 membrane raft
GO:0048471 perinuclear region of cytoplasm
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0050728 negative regulation of inflammatory response
GO:0050779 RNA destabilization
GO:0051044 positive regulation of membrane protein ectodomain proteolysis
GO:0060548 negative regulation of cell death
GO:0071222 cellular response to lipopolysaccharide
GO:0071363 cellular response to growth factor stimulus
GO:0097191 extrinsic apoptotic signaling pathway
GO:0150077 regulation of neuroinflammatory response
GO:0150079 negative regulation of neuroinflammatory response
GO:0150098 glial cell-neuron signaling
GO:1901215 negative regulation of neuron death
GO:1902339 positive regulation of apoptotic process involved in morphogenesis
GO:2001141 regulation of RNA biosynthetic process

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001368 TNFR/NGFR cysteine-rich regionDomainDomain
IPR020411 Tumour necrosis factor receptor 1BFamilyFamily
IPR033996 Tumor necrosis factor receptor 1B, N-terminalDomainDomain

Diseases

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Interactions

5 interactions