Entity Details

Primary name PO2F1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP25425
EntryNamePO2F1_MOUSE
FullNamePOU domain, class 2, transcription factor 1
TaxID10090
Evidenceevidence at protein level
Length770
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesPou2f1

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005783 endoplasmic reticulum
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010629 negative regulation of gene expression
GO:0030910 olfactory placode formation
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060235 lens induction in camera-type eye
GO:0090575 RNA polymerase II transcription regulator complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000327 POU-specific domainDomainDomain
IPR000972 Octamer-binding transcription factorFamilyFamily
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR010982 Lambda repressor-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR013847 POU domainDomainDomain
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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