Entity Details

Primary name TNR6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP25446
EntryNameTNR6_MOUSE
FullNameTumor necrosis factor receptor superfamily member 6
TaxID10090
Evidenceevidence at protein level
Length327
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesFas

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0002020 protease binding
GO:0005031 tumor necrosis factor-activated receptor activity
GO:0005516 calmodulin binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0006924 activation-induced cell death of T cells
GO:0006925 inflammatory cell apoptotic process
GO:0007623 circadian rhythm
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0009636 response to toxic substance
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010467 gene expression
GO:0010468 regulation of gene expression
GO:0010626 negative regulation of Schwann cell proliferation
GO:0010942 positive regulation of cell death
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016604 nuclear body
GO:0019724 B cell mediated immunity
GO:0019900 kinase binding
GO:0030141 secretory granule
GO:0031104 dendrite regeneration
GO:0031264 death-inducing signaling complex
GO:0031265 CD95 death-inducing signaling complex
GO:0031334 positive regulation of protein-containing complex assembly
GO:0032872 regulation of stress-activated MAPK cascade
GO:0034198 cellular response to amino acid starvation
GO:0036337 Fas signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042383 sarcolemma
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0045060 negative thymic T cell selection
GO:0045121 membrane raft
GO:0045619 regulation of lymphocyte differentiation
GO:0045637 regulation of myeloid cell differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0048536 spleen development
GO:0050869 negative regulation of B cell activation
GO:0051384 response to glucocorticoid
GO:0051402 neuron apoptotic process
GO:0070227 lymphocyte apoptotic process
GO:0071285 cellular response to lithium ion
GO:0071455 cellular response to hyperoxia
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097049 motor neuron apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097284 hepatocyte apoptotic process
GO:0097440 apical dendrite
GO:0097527 necroptotic signaling pathway
GO:1900148 negative regulation of Schwann cell migration
GO:2001235 positive regulation of apoptotic signaling pathway
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Membrane raft

Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR001368 TNFR/NGFR cysteine-rich regionDomainDomain
IPR008063 Fas receptorFamilyFamily
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR033998 Fas receptor, death domainDomainDomain
IPR033999 Fas receptor, N-terminalDomainDomain

Diseases

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