Entity Details

Primary name BMI1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP25916
EntryNameBMI1_MOUSE
FullNamePolycomb complex protein BMI-1
TaxID10090
Evidenceevidence at protein level
Length324
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesBmi1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000151 ubiquitin ligase complex
GO:0000792 heterochromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001501 skeletal system development
GO:0001701 in utero embryonic development
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006306 DNA methylation
GO:0006342 chromatin silencing
GO:0006959 humoral immune response
GO:0007420 brain development
GO:0008270 zinc ion binding
GO:0009987 cellular process
GO:0016573 histone acetylation
GO:0016574 histone ubiquitination
GO:0016604 nuclear body
GO:0021903 rostrocaudal neural tube patterning
GO:0030890 positive regulation of B cell proliferation
GO:0031519 PcG protein complex
GO:0033092 positive regulation of immature T cell proliferation in thymus
GO:0035102 PRC1 complex
GO:0036353 histone H2A-K119 monoubiquitination
GO:0043565 sequence-specific DNA binding
GO:0045814 negative regulation of gene expression, epigenetic
GO:0048103 somatic stem cell division
GO:0048704 embryonic skeletal system morphogenesis
GO:0048706 embryonic skeletal system development
GO:0051443 positive regulation of ubiquitin-protein transferase activity
GO:0061484 hematopoietic stem cell homeostasis
GO:0071347 cellular response to interleukin-1
GO:0071549 cellular response to dexamethasone stimulus
GO:0097027 ubiquitin-protein transferase activator activity
GO:1990841 promoter-specific chromatin binding
GO:2000011 regulation of adaxial/abaxial pattern formation
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR032443 RAWUL domainDomainDomain

Diseases

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