Entity Details

Primary name ADRB3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP25962
EntryNameADRB3_MOUSE
FullNameBeta-3 adrenergic receptor
TaxID10090
Evidenceevidence at transcript level
Length400
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesAdrb3

GO terms

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GOName
GO:0002024 diet induced thermogenesis
GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
GO:0004930 G protein-coupled receptor activity
GO:0004939 beta-adrenergic receptor activity
GO:0005634 nucleus
GO:0005887 integral component of plasma membrane
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007568 aging
GO:0009409 response to cold
GO:0015052 beta3-adrenergic receptor activity
GO:0016020 membrane
GO:0031649 heat generation
GO:0031699 beta-3 adrenergic receptor binding
GO:0040015 negative regulation of multicellular organism growth
GO:0042755 eating behavior
GO:0042803 protein homodimerization activity
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0046677 response to antibiotic
GO:0050873 brown fat cell differentiation
GO:0051379 epinephrine binding
GO:0051380 norepinephrine binding
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000681 Beta 3 adrenoceptorFamilyFamily
IPR002233 Adrenoceptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ADRB3_MOUSESRC_HUMANBioGRID, MINT11013230 details
ADRB3_MOUSECAV3_MOUSEIntAct24190960 details