Entity Details

Primary name TLN1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP26039
EntryNameTLN1_MOUSE
FullNameTalin-1
TaxID10090
Evidenceevidence at protein level
Length2541
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesTln1

GO terms

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GOName
GO:0001726 ruffle
GO:0001786 phosphatidylserine binding
GO:0005178 integrin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005925 focal adhesion
GO:0007044 cell-substrate junction assembly
GO:0007229 integrin-mediated signaling pathway
GO:0009986 cell surface
GO:0017166 vinculin binding
GO:0030274 LIM domain binding
GO:0030866 cortical actin cytoskeleton organization
GO:0032587 ruffle membrane
GO:0033622 integrin activation
GO:0035091 phosphatidylinositol binding
GO:0051015 actin filament binding
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cell surface
Cytoplasm

Domains

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DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR002558 I/LWEQ domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR015009 Vinculin-binding site-containing domainDomainDomain
IPR015224 Talin, centralDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR032425 Talin, N-terminal F0 domainDomainDomain
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR035964 I/LWEQ domain superfamilyFamilyHomologous superfamily
IPR036476 Talin, central domain superfamilyFamilyHomologous superfamily
IPR036723 Alpha-catenin/vinculin-like superfamilyFamilyHomologous superfamily
IPR037438 Talin-1/2, rod-segmentDomainDomain

Diseases

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