Entity Details

Primary name EZRI_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP26040
EntryNameEZRI_MOUSE
FullNameEzrin
TaxID10090
Evidenceevidence at protein level
Length586
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesEzr

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001650 fibrillar center
GO:0001726 ruffle
GO:0001772 immunological synapse
GO:0001931 uropod
GO:0001951 intestinal D-glucose absorption
GO:0003376 sphingosine-1-phosphate receptor signaling pathway
GO:0003779 actin binding
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005903 brush border
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007159 leukocyte cell-cell adhesion
GO:0008017 microtubule binding
GO:0008022 protein C-terminus binding
GO:0008360 regulation of cell shape
GO:0010628 positive regulation of gene expression
GO:0010737 protein kinase A signaling
GO:0015629 actin cytoskeleton
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019898 extrinsic component of membrane
GO:0019904 protein domain specific binding
GO:0022614 membrane to membrane docking
GO:0030175 filopodium
GO:0030315 T-tubule
GO:0030953 astral microtubule organization
GO:0031528 microvillus membrane
GO:0031532 actin cytoskeleton reorganization
GO:0031623 receptor internalization
GO:0032532 regulation of microvillus length
GO:0032587 ruffle membrane
GO:0032703 negative regulation of interleukin-2 production
GO:0032991 protein-containing complex
GO:0034236 protein kinase A catalytic subunit binding
GO:0034237 protein kinase A regulatory subunit binding
GO:0034629 cellular protein-containing complex localization
GO:0035088 establishment or maintenance of apical/basal cell polarity
GO:0036064 ciliary basal body
GO:0040018 positive regulation of multicellular organism growth
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043209 myelin sheath
GO:0043622 cortical microtubule organization
GO:0044297 cell body
GO:0044393 microspike
GO:0044548 S100 protein binding
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045177 apical part of cell
GO:0046847 filopodium assembly
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048471 perinuclear region of cytoplasm
GO:0050714 positive regulation of protein secretion
GO:0050839 cell adhesion molecule binding
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0051015 actin filament binding
GO:0051017 actin filament bundle assembly
GO:0051018 protein kinase A binding
GO:0051117 ATPase binding
GO:0051286 cell tip
GO:0051660 establishment of centrosome localization
GO:0061028 establishment of endothelial barrier
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071320 cellular response to cAMP
GO:0071944 cell periphery
GO:0072659 protein localization to plasma membrane
GO:0072697 protein localization to cell cortex
GO:0097449 astrocyte projection
GO:0097454 Schwann cell microvillus
GO:0097718 disordered domain specific binding
GO:0098592 cytoplasmic side of apical plasma membrane
GO:1902115 regulation of organelle assembly
GO:1902896 terminal web assembly
GO:1902966 positive regulation of protein localization to early endosome
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1903364 positive regulation of cellular protein catabolic process
GO:1903753 negative regulation of p38MAPK cascade
GO:2000643 positive regulation of early endosome to late endosome transport

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR000798 Ezrin/radixin/moesin-likeFamilyFamily
IPR008954 Moesin tail domain superfamilyFamilyHomologous superfamily
IPR011174 Ezrin/radixin/moesinFamilyFamily
IPR011259 Ezrin/radixin/moesin, C-terminalDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR041789 ERM family, FERM domain C-lobeDomainDomain

Diseases

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