Entity Details

Primary name FCGR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP26151
EntryNameFCGR1_MOUSE
FullNameHigh affinity immunoglobulin gamma Fc receptor I
TaxID10090
Evidenceevidence at protein level
Length404
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesFcgr1

GO terms

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GOName
GO:0001788 antibody-dependent cellular cytotoxicity
GO:0001798 positive regulation of type IIa hypersensitivity
GO:0001805 positive regulation of type III hypersensitivity
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0007166 cell surface receptor signaling pathway
GO:0009617 response to bacterium
GO:0009897 external side of plasma membrane
GO:0019770 IgG receptor activity
GO:0019864 IgG binding
GO:0019884 antigen processing and presentation of exogenous antigen
GO:0031774 leukotriene receptor binding
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0050766 positive regulation of phagocytosis
GO:0050776 regulation of immune response
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0061098 positive regulation of protein tyrosine kinase activity

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
FCGR1_MOUSEHCK_MOUSEBioGRID19380812 details