Entity Details

Primary name S10A8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP27005
EntryNameS10A8_MOUSE
FullNameProtein S100-A8
TaxID10090
Evidenceevidence at protein level
Length89
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesS100a8

GO terms

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GOName
GO:0002523 leukocyte migration involved in inflammatory response
GO:0002793 positive regulation of peptide secretion
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006914 autophagy
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0014002 astrocyte development
GO:0016209 antioxidant activity
GO:0018119 peptidyl-cysteine S-nitrosylation
GO:0030593 neutrophil chemotaxis
GO:0032496 response to lipopolysaccharide
GO:0035425 autocrine signaling
GO:0035662 Toll-like receptor 4 binding
GO:0045087 innate immune response
GO:0045111 intermediate filament cytoskeleton
GO:0048306 calcium-dependent protein binding
GO:0050544 arachidonic acid binding
GO:0050729 positive regulation of inflammatory response
GO:0050786 RAGE receptor binding
GO:0070488 neutrophil aggregation
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001751 S100/Calbindin-D9k, conserved siteSiteConserved site
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR013787 S100/CaBP-9k-type, calcium binding, subdomainDomainDomain
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR028474 Protein S100-A8FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
S10A8_MOUSES10A9_MOUSEIntAct9867828 details
S10A8_MOUSES10A8_MOUSEIntAct9867828 details