Entity Details

Primary name AVR2B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP27040
EntryNameAVR2B_MOUSE
FullNameActivin receptor type-2B
TaxID10090
Evidenceevidence at protein level
Length536
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesAcvr2b

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001501 skeletal system development
GO:0001702 gastrulation with mouth forming second
GO:0001822 kidney development
GO:0001946 lymphangiogenesis
GO:0001974 blood vessel remodeling
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007368 determination of left/right symmetry
GO:0007389 pattern specification process
GO:0007498 mesoderm development
GO:0007507 heart development
GO:0009749 response to glucose
GO:0009791 post-embryonic development
GO:0009952 anterior/posterior pattern specification
GO:0009966 regulation of signal transduction
GO:0017002 activin-activated receptor activity
GO:0019838 growth factor binding
GO:0030073 insulin secretion
GO:0030324 lung development
GO:0030501 positive regulation of bone mineralization
GO:0030509 BMP signaling pathway
GO:0031016 pancreas development
GO:0032147 activation of protein kinase activity
GO:0032924 activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0032991 protein-containing complex
GO:0034711 inhibin binding
GO:0035265 organ growth
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043235 receptor complex
GO:0045669 positive regulation of osteoblast differentiation
GO:0046872 metal ion binding
GO:0048179 activin receptor complex
GO:0048185 activin binding
GO:0048617 embryonic foregut morphogenesis
GO:0048705 skeletal system morphogenesis
GO:0060021 roof of mouth development
GO:0060836 lymphatic endothelial cell differentiation
GO:0060840 artery development
GO:0060841 venous blood vessel development
GO:0061298 retina vasculature development in camera-type eye
GO:0071363 cellular response to growth factor stimulus
GO:0120163 negative regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000333 Ser/Thr protein kinase, TGFB receptorFamilyFamily
IPR000472 Activin types I and II receptor domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions