Entity Details

Primary name IQGA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86VI3
EntryNameIQGA3_HUMAN
FullNameRas GTPase-activating-like protein IQGAP3
TaxID9606
Evidenceevidence at protein level
Length1631
SequenceStatuscomplete
DateCreated2004-06-21
DateModified2021-06-02

Ontological Relatives

GenesIQGAP3

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000187 obsolete activation of MAPK activity
GO:0005096 GTPase activator activity
GO:0005516 calmodulin binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005911 cell-cell junction
GO:0007265 Ras protein signal transduction
GO:0008361 regulation of cell size
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016328 lateral plasma membrane
GO:0031267 small GTPase binding
GO:0032956 regulation of actin cytoskeleton organization
GO:0033601 positive regulation of mammary gland epithelial cell proliferation
GO:0051015 actin filament binding
GO:0070371 ERK1 and ERK2 cascade
GO:0070856 myosin VI light chain binding
GO:0071310 cellular response to organic substance

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR000593 RasGAP protein, C-terminalDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001936 Ras GTPase-activating domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR023152 Ras GTPase-activating protein, conserved siteSiteConserved site
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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