Entity Details

Primary name GNA12_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP27600
EntryNameGNA12_MOUSE
FullNameGuanine nucleotide-binding protein subunit alpha-12
TaxID10090
Evidenceevidence at protein level
Length379
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesGna12

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0001701 in utero embryonic development
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005834 heterotrimeric G-protein complex
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007266 Rho protein signal transduction
GO:0008360 regulation of cell shape
GO:0010762 regulation of fibroblast migration
GO:0016328 lateral plasma membrane
GO:0030154 cell differentiation
GO:0031526 brush border membrane
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0031752 D5 dopamine receptor binding
GO:0032006 regulation of TOR signaling
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 intracellular signal transduction
GO:0042493 response to drug
GO:0042733 embryonic digit morphogenesis
GO:0046872 metal ion binding
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1904753 negative regulation of vascular associated smooth muscle cell migration

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Lateral cell membrane

Domains

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DomainNameCategoryType
IPR000469 G-protein alpha subunit, group 12/13FamilyFamily
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunitFamilyFamily
IPR011025 G protein alpha subunit, helical insertionFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GNA12_MOUSE2AAA_HUMANMINT15525651 details