Entity Details

Primary name XRCC5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP27641
EntryNameXRCC5_MOUSE
FullNameX-ray repair cross-complementing protein 5
TaxID10090
Evidenceevidence at protein level
Length732
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesXrcc5

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000781 chromosome, telomeric region
GO:0000976 transcription cis-regulatory region binding
GO:0002218 activation of innate immune response
GO:0003678 DNA helicase activity
GO:0003684 damaged DNA binding
GO:0003691 double-stranded telomeric DNA binding
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006310 DNA recombination
GO:0006974 cellular response to DNA damage stimulus
GO:0007420 brain development
GO:0008022 protein C-terminus binding
GO:0008094 ATPase, acting on DNA
GO:0008283 cell population proliferation
GO:0031625 ubiquitin protein ligase binding
GO:0032040 small-subunit processome
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032991 protein-containing complex
GO:0032993 protein-DNA complex
GO:0034462 small-subunit processome assembly
GO:0034511 U3 snoRNA binding
GO:0042162 telomeric DNA binding
GO:0042493 response to drug
GO:0043564 Ku70:Ku80 complex
GO:0044877 protein-containing complex binding
GO:0045027 DNA end binding
GO:0045087 innate immune response
GO:0045860 positive regulation of protein kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048660 regulation of smooth muscle cell proliferation
GO:0050769 positive regulation of neurogenesis
GO:0051575 5'-deoxyribose-5-phosphate lyase activity
GO:0060218 hematopoietic stem cell differentiation
GO:0070419 nonhomologous end joining complex
GO:0071398 cellular response to fatty acid
GO:0071475 cellular hyperosmotic salinity response
GO:0071480 cellular response to gamma radiation
GO:0071481 cellular response to X-ray
GO:0090734 site of DNA damage
GO:1904430 negative regulation of t-circle formation
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR005160 Ku70/Ku80 C-terminal armDomainDomain
IPR005161 Ku70/Ku80, N-terminal alpha/betaDomainDomain
IPR006164 Ku70/Ku80 beta-barrel domainDomainDomain
IPR014893 Ku, C-terminalDomainDomain
IPR016194 SPOC-like, C-terminal domain superfamilyFamilyHomologous superfamily
IPR024193 Ku80FamilyFamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR036494 Ku, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
XRCC5_MOUSEBIN1_HUMANBioGRID17671430 details