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Entity Details
Primary name
H2AX_MOUSE
Entity type
UniProt
Source
Source Link
Details
Accession
P27661
EntryName
H2AX_MOUSE
FullName
Histone H2AX
TaxID
10090
Evidence
evidence at protein level
Length
143
SequenceStatus
complete
DateCreated
1992-08-01
DateModified
2021-06-02
Ontological Relatives
Genes
H2ax
GO terms
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GO
Name
GO:0000724
double-strand break repair via homologous recombination
GO:0000781
chromosome, telomeric region
GO:0000785
chromatin
GO:0000786
nucleosome
GO:0000794
condensed nuclear chromosome
GO:0001673
male germ cell nucleus
GO:0001741
XY body
GO:0003677
DNA binding
GO:0003684
damaged DNA binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005657
replication fork
GO:0005694
chromosome
GO:0005813
centrosome
GO:0006281
DNA repair
GO:0006342
chromatin silencing
GO:0006974
cellular response to DNA damage stimulus
GO:0007283
spermatogenesis
GO:0016607
nuclear speck
GO:0019899
enzyme binding
GO:0021987
cerebral cortex development
GO:0035861
site of double-strand break
GO:0042393
histone binding
GO:0046982
protein heterodimerization activity
GO:0051321
meiotic cell cycle
GO:0071480
cellular response to gamma radiation
GO:0090398
cellular senescence
GO:0090734
site of DNA damage
Subcellular Location
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Subcellular Location
Chromosome
Nucleus
Domains
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Domain
Name
Category
Type
IPR002119
Histone H2A
Family
Family
IPR007125
Histone H2A/H2B/H3
Domain
Domain
IPR009072
Histone-fold
Family
Homologous superfamily
IPR032454
Histone H2A, C-terminal domain
Domain
Domain
IPR032458
Histone H2A conserved site
Site
Conserved site
Diseases
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Drugs
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Interactions
20 interactions
Interactor
Partner
Sources
Publications
Link
H2AX_MOUSE
ATM_HUMAN
BioGRID
15632067
details
H2AX_MOUSE
ATM_MOUSE
BioGRID
11571274
details
H2AX_MOUSE
ITA2B_MOUSE
BioGRID
30333137
details
H2AX_MOUSE
FACD2_MOUSE
BioGRID, MINT
17304220
details
H2AX_MOUSE
RNF8_HUMAN
IntAct
18001825
details
H2AX_MOUSE
AIFM1_MOUSE
MINT
20360685
details
H2AX_MOUSE
PARP1_MOUSE
MINT
20442707
details
H2AX_MOUSE
TOPB1_MOUSE
MINT
20871591
details
H2AX_MOUSE
TP53B_MOUSE
BioGRID, MINT
12792649
20871591
details
H2AX_MOUSE
PSME4_MOUSE
IntAct
23706739
details
H2AX_MOUSE
LMNA_HUMAN
IntAct
23658700
details
H2AX_MOUSE
LMNA_MOUSE
IntAct
23658700
details
H2AX_MOUSE
NBN_HUMAN
BioGRID
12792649
details
H2AX_MOUSE
TP53B_HUMAN
BioGRID
12792649
details
H2AX_MOUSE
NBN_MOUSE
BioGRID
12792649
details
H2AX_MOUSE
MDC1_MOUSE
BioGRID
25703348
details
H2AX_MOUSE
PSIP1_MOUSE
BioGRID
25703348
details
H2AX_MOUSE
SRRM2_MOUSE
BioGRID
25703348
details
H2AX_MOUSE
HSP72_MOUSE
BioGRID
25703348
details
H2AX_MOUSE
SP16H_MOUSE
BioGRID
25703348
details
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