Entity Details

Primary name DMA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP28078
EntryNameDMA_MOUSE
FullNameClass II histocompatibility antigen, M alpha chain
TaxID10090
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0002503 peptide antigen assembly with MHC class II protein complex
GO:0002636 positive regulation of germinal center formation
GO:0002922 positive regulation of humoral immune response
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0005771 multivesicular body
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0015031 protein transport
GO:0016021 integral component of membrane
GO:0016064 immunoglobulin mediated immune response
GO:0019882 antigen processing and presentation
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 MHC class II protein complex binding
GO:0031902 late endosome membrane
GO:0042613 MHC class II protein complex
GO:0043231 intracellular membrane-bounded organelle
GO:0045059 positive thymic T cell selection
GO:0045582 positive regulation of T cell differentiation
GO:0048839 inner ear development
GO:0050778 positive regulation of immune response
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0065003 protein-containing complex assembly

Subcellular Location

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Subcellular Location
Late endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR001003 MHC class II, alpha chain, N-terminalDomainDomain
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014745 MHC class II, alpha/beta chain, N-terminalFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink