Entity Details - PICKLE: A Protein InteraCtion KnowLedgebasE

Accession	P28271
EntryName	ACOC_MOUSE
FullName	Cytoplasmic aconitate hydratase
TaxID	10090
Evidence	evidence at protein level
Length	889
SequenceStatus	complete
DateCreated	1992-12-01
DateModified	2021-06-02

Genes

Aco1

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GO	Name
GO:0003723	RNA binding
GO:0003994	aconitate hydratase activity
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0006099	tricarboxylic acid cycle
GO:0006101	citrate metabolic process
GO:0006417	regulation of translation
GO:0006879	cellular iron ion homeostasis
GO:0009791	post-embryonic development
GO:0010040	response to iron(II) ion
GO:0010468	regulation of gene expression
GO:0030350	iron-responsive element binding
GO:0043231	intracellular membrane-bounded organelle
GO:0046872	metal ion binding
GO:0047780	citrate dehydratase activity
GO:0048027	mRNA 5'-UTR binding
GO:0050892	intestinal absorption
GO:0051536	iron-sulfur cluster binding
GO:0051538	3 iron, 4 sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

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Subcellular Location
Cytoplasm

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Domain	Name	Category	Type
IPR000573	Aconitase A/isopropylmalate dehydratase small subunit, swivel domain	Domain	Domain
IPR001030	Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain	Domain	Domain
IPR006249	Aconitase/Iron-responsive element-binding protein 2	Family	Family
IPR015928	Aconitase/3-isopropylmalate dehydratase, swivel	Family	Homologous superfamily
IPR015931	Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3	Family	Homologous superfamily
IPR018136	Aconitase family, 4Fe-4S cluster binding site	Site	Binding site
IPR029784	Iron regulatory protein 1	Family	Family
IPR036008	Aconitase, iron-sulfur domain	Family	Homologous superfamily
IPR044137	Aconitase A, swivel domain	Domain	Domain

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0 interactions

Interactor	Partner	Sources	Publications	Link