Entity Details

Primary name 5HT1B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP28334
EntryName5HT1B_MOUSE
FullName5-hydroxytryptamine receptor 1B
TaxID10090
Evidenceevidence at transcript level
Length386
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesHtr1b

GO terms

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GOName
GO:0002031 G protein-coupled receptor internalization
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007631 feeding behavior
GO:0014053 negative regulation of gamma-aminobutyric acid secretion
GO:0014059 regulation of dopamine secretion
GO:0014063 negative regulation of serotonin secretion
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0032229 negative regulation of synaptic transmission, GABAergic
GO:0035690 cellular response to drug
GO:0042220 response to cocaine
GO:0042310 vasoconstriction
GO:0042756 drinking behavior
GO:0044305 calyx of Held
GO:0045471 response to ethanol
GO:0046849 bone remodeling
GO:0050795 regulation of behavior
GO:0051378 serotonin binding
GO:0051385 response to mineralocorticoid
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0071312 cellular response to alkaloid
GO:0071502 cellular response to temperature stimulus
GO:0098666 G protein-coupled serotonin receptor complex
GO:0099056 integral component of presynaptic membrane
GO:0099154 serotonergic synapse
GO:0099171 presynaptic modulation of chemical synaptic transmission
GO:0099626 voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR002147 5-Hydroxytryptamine 1B receptorFamilyFamily
IPR002231 5-hydroxytryptamine receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

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