Entity Details

Primary name RPTOR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N122
EntryNameRPTOR_HUMAN
FullNameRegulatory-associated protein of mTOR
TaxID9606
Evidenceevidence at protein level
Length1335
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesRPTOR

GO terms

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GOName
GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding
GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0001156 TFIIIC-class transcription factor complex binding
GO:0001558 regulation of cell growth
GO:0001938 positive regulation of endothelial cell proliferation
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0008361 regulation of cell size
GO:0009267 cellular response to starvation
GO:0009410 response to xenobiotic stimulus
GO:0010494 cytoplasmic stress granule
GO:0010506 regulation of autophagy
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0016032 viral process
GO:0016241 regulation of macroautophagy
GO:0019901 protein kinase binding
GO:0030291 protein serine/threonine kinase inhibitor activity
GO:0030295 protein kinase activator activity
GO:0030307 positive regulation of cell growth
GO:0030425 dendrite
GO:0030674 protein-macromolecule adaptor activity
GO:0031669 cellular response to nutrient levels
GO:0031929 TOR signaling
GO:0031931 TORC1 complex
GO:0032008 positive regulation of TOR signaling
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034198 cellular response to amino acid starvation
GO:0035176 social behavior
GO:0038202 TORC1 signaling
GO:0043025 neuronal cell body
GO:0044877 protein-containing complex binding
GO:0045945 positive regulation of transcription by RNA polymerase III
GO:0071230 cellular response to amino acid stimulus
GO:0071233 cellular response to leucine
GO:0071889 14-3-3 protein binding
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:1900034 regulation of cellular response to heat
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic granule
Lysosome

Domains

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DomainNameCategoryType
IPR000357 HEAT repeatRepeatRepeat
IPR001680 WD40 repeatRepeatRepeat
IPR004083 Regulatory associated protein of TORFamilyFamily
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR029347 Raptor, N-terminal CASPase-like domainDomainDomain
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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