Entity Details

Primary name RXRA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP28700
EntryNameRXRA_MOUSE
FullNameRetinoic acid receptor RXR-alpha
TaxID10090
Evidenceevidence at protein level
Length467
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesRxra

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001701 in utero embryonic development
GO:0001890 placenta development
GO:0001893 maternal placenta development
GO:0001972 retinoic acid binding
GO:0003007 heart morphogenesis
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007507 heart development
GO:0007566 embryo implantation
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0010629 negative regulation of gene expression
GO:0016922 nuclear receptor binding
GO:0019048 modulation by virus of host process
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0030154 cell differentiation
GO:0030424 axon
GO:0031490 chromatin DNA binding
GO:0031641 regulation of myelination
GO:0032526 response to retinoic acid
GO:0035357 peroxisome proliferator activated receptor signaling pathway
GO:0042277 peptide binding
GO:0042802 identical protein binding
GO:0042809 vitamin D receptor binding
GO:0042974 retinoic acid receptor binding
GO:0043010 camera-type eye development
GO:0043065 positive regulation of apoptotic process
GO:0043235 receptor complex
GO:0043565 sequence-specific DNA binding
GO:0044323 retinoic acid-responsive element binding
GO:0044877 protein-containing complex binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045994 positive regulation of translational initiation by iron
GO:0048384 retinoic acid receptor signaling pathway
GO:0048856 anatomical structure development
GO:0050692 DNA binding domain binding
GO:0050693 LBD domain binding
GO:0051384 response to glucocorticoid
GO:0055007 cardiac muscle cell differentiation
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0055012 ventricular cardiac muscle cell differentiation
GO:0060038 cardiac muscle cell proliferation
GO:0060485 mesenchyme development
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060687 regulation of branching involved in prostate gland morphogenesis
GO:0060978 angiogenesis involved in coronary vascular morphogenesis
GO:0061032 visceral serous pericardium development
GO:0090575 RNA polymerase II transcription regulator complex
GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR000003 Retinoid X receptor/HNF4FamilyFamily
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR021780 Nuclear/hormone receptor activator site AF-1DomainDomain
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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