Entity Details

Primary name EPHA3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP29319
EntryNameEPHA3_MOUSE
FullNameEphrin type-A receptor 3
TaxID10090
Evidenceevidence at protein level
Length983
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0003197 endocardial cushion development
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005003 ephrin receptor activity
GO:0005004 GPI-linked ephrin receptor activity
GO:0005005 transmembrane-ephrin receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007411 axon guidance
GO:0010717 regulation of epithelial to mesenchymal transition
GO:0010976 positive regulation of neuron projection development
GO:0010977 negative regulation of neuron projection development
GO:0015629 actin cytoskeleton
GO:0016477 cell migration
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019838 growth factor binding
GO:0030334 regulation of cell migration
GO:0031965 nuclear membrane
GO:0032956 regulation of actin cytoskeleton organization
GO:0033674 positive regulation of kinase activity
GO:0043005 neuron projection
GO:0043087 regulation of GTPase activity
GO:0043235 receptor complex
GO:0045806 negative regulation of endocytosis
GO:0048013 ephrin receptor signaling pathway
GO:0051893 regulation of focal adhesion assembly
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0071300 cellular response to retinoic acid
GO:0071372 cellular response to follicle-stimulating hormone stimulus
GO:0097155 fasciculation of sensory neuron axon
GO:0097156 fasciculation of motor neuron axon
GO:0098793 presynapse
GO:0098982 GABA-ergic synapse
GO:0099560 synaptic membrane adhesion
GO:1903078 positive regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001090 Ephrin receptor ligand binding domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001426 Tyrosine-protein kinase, receptor class V, conserved siteSiteConserved site
IPR001660 Sterile alpha motif domainDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-likeDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016257 Ephrin receptor type-A /type-BFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR027936 Ephrin receptor, transmembrane domainDomainDomain
IPR034266 Ephrin type-A receptor 3, ligand binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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