Entity Details

Primary name AGTRA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP29754
EntryNameAGTRA_MOUSE
FullNameType-1A angiotensin II receptor
TaxID10090
Evidenceevidence at protein level
Length359
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesAgtr1a

GO terms

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GOName
GO:0001568 blood vessel development
GO:0001596 angiotensin type I receptor activity
GO:0001819 positive regulation of cytokine production
GO:0001822 kidney development
GO:0001921 positive regulation of receptor recycling
GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0002001 renin secretion into blood stream
GO:0002018 renin-angiotensin regulation of aldosterone production
GO:0002019 regulation of renal output by angiotensin
GO:0002035 brain renin-angiotensin system
GO:0004930 G protein-coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006885 regulation of pH
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007266 Rho protein signal transduction
GO:0007507 heart development
GO:0007568 aging
GO:0008284 positive regulation of cell population proliferation
GO:0009651 response to salt stress
GO:0010873 positive regulation of cholesterol esterification
GO:0012505 endomembrane system
GO:0014823 response to activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0019229 regulation of vasoconstriction
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0030425 dendrite
GO:0031410 cytoplasmic vesicle
GO:0031711 bradykinin receptor binding
GO:0031748 D1 dopamine receptor binding
GO:0031968 organelle outer membrane
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032430 positive regulation of phospholipase A2 activity
GO:0032930 positive regulation of superoxide anion generation
GO:0034391 regulation of smooth muscle cell apoptotic process
GO:0034392 negative regulation of smooth muscle cell apoptotic process
GO:0038166 angiotensin-activated signaling pathway
GO:0042310 vasoconstriction
GO:0042416 dopamine biosynthetic process
GO:0042756 drinking behavior
GO:0042976 activation of Janus kinase activity
GO:0043627 response to estrogen
GO:0045777 positive regulation of blood pressure
GO:0046982 protein heterodimerization activity
GO:0051412 response to corticosterone
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0055037 recycling endosome
GO:0060326 cell chemotaxis
GO:0071549 cellular response to dexamethasone stimulus
GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:1905665 positive regulation of calcium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000190 Angiotensin II receptor type 1FamilyFamily
IPR000248 Angiotensin II receptor familyFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
AGTRA_MOUSEATRAP_MOUSEBioGRID, IntAct, MINT10358057 15757644 details
AGTRA_MOUSEANKR1_MOUSEMINT24515436 details
AGTRA_MOUSEARRB1_MOUSEBioGRID11579203 details