Entity Details

Primary name AL5AP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP30355
EntryNameAL5AP_MOUSE
FullNameArachidonate 5-lipoxygenase-activating protein
TaxID10090
Evidenceevidence at protein level
Length161
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesAlox5ap

GO terms

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GOName
GO:0002540 leukotriene production involved in inflammatory response
GO:0002675 positive regulation of acute inflammatory response
GO:0004051 arachidonate 5-lipoxygenase activity
GO:0004364 glutathione transferase activity
GO:0004464 leukotriene-C4 synthase activity
GO:0004602 glutathione peroxidase activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0008047 enzyme activator activity
GO:0016021 integral component of membrane
GO:0019370 leukotriene biosynthetic process
GO:0019372 lipoxygenase pathway
GO:0019899 enzyme binding
GO:0031965 nuclear membrane
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
GO:0047485 protein N-terminus binding
GO:0050544 arachidonic acid binding
GO:0070207 protein homotrimerization
GO:0071277 cellular response to calcium ion

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Nucleus membrane

Domains

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DomainNameCategoryType
IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) proteinFamilyFamily
IPR001446 5-lipoxygenase-activating proteinFamilyFamily
IPR018295 FLAP/GST2/LTC4S, conserved siteSiteConserved site
IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AL5AP_MOUSELOX5_MOUSEBioGRID19075240 details