Entity Details

Primary name ADA2B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP30545
EntryNameADA2B_MOUSE
FullNameAlpha-2B adrenergic receptor
TaxID10090
Evidenceevidence at protein level
Length453
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesAdra2b

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000187 obsolete activation of MAPK activity
GO:0001525 angiogenesis
GO:0003056 regulation of vascular associated smooth muscle contraction
GO:0004930 G protein-coupled receptor activity
GO:0004935 adrenergic receptor activity
GO:0004938 alpha2-adrenergic receptor activity
GO:0005829 cytosol
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007565 female pregnancy
GO:0009986 cell surface
GO:0030168 platelet activation
GO:0032148 activation of protein kinase B activity
GO:0035624 receptor transactivation
GO:0043231 intracellular membrane-bounded organelle
GO:0043410 positive regulation of MAPK cascade
GO:0045666 positive regulation of neuron differentiation
GO:0045777 positive regulation of blood pressure
GO:0051379 epinephrine binding
GO:0070474 positive regulation of uterine smooth muscle contraction
GO:0071875 adrenergic receptor signaling pathway
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000207 Alpha 2B adrenoceptorFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR002233 Adrenoceptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ADA2B_MOUSEEI2BA_HUMANIntAct9235896 details