Entity Details

Primary name PE2R3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP30557
EntryNamePE2R3_MOUSE
FullNameProstaglandin E2 receptor EP3 subtype
TaxID10090
Evidenceevidence at protein level
Length365
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GO terms

Show/Hide Table
GOName
GO:0001660 fever generation
GO:0001934 positive regulation of protein phosphorylation
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0004957 prostaglandin E receptor activity
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010700 negative regulation of norepinephrine secretion
GO:0010840 regulation of circadian sleep/wake cycle, wakefulness
GO:0014061 regulation of norepinephrine secretion
GO:0014827 intestine smooth muscle contraction
GO:0014832 urinary bladder smooth muscle contraction
GO:0015701 bicarbonate transport
GO:0016021 integral component of membrane
GO:0031526 brush border membrane
GO:0031622 positive regulation of fever generation
GO:0031623 receptor internalization
GO:0031965 nuclear membrane
GO:0032496 response to lipopolysaccharide
GO:0035810 positive regulation of urine volume
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0045907 positive regulation of vasoconstriction
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046676 negative regulation of insulin secretion
GO:0060455 negative regulation of gastric acid secretion
GO:0090331 negative regulation of platelet aggregation
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1903170 negative regulation of calcium ion transmembrane transport
GO:1903640 negative regulation of gastrin-induced gastric acid secretion
GO:1904320 positive regulation of smooth muscle contraction involved in micturition
GO:1904322 cellular response to forskolin
GO:1904325 positive regulation of inhibitory G protein-coupled receptor phosphorylation
GO:1904326 negative regulation of circadian sleep/wake cycle, wakefulness
GO:1904330 positive regulation of myofibroblast contraction
GO:1904343 positive regulation of colon smooth muscle contraction
GO:1904346 positive regulation of gastric mucosal blood circulation
GO:1990767 prostaglandin receptor internalization
GO:1990769 proximal neuron projection
GO:2000391 positive regulation of neutrophil extravasation
GO:2000978 negative regulation of forebrain neuron differentiation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000154 Prostanoid EP3 receptor type 3FamilyFamily
IPR000265 Prostanoid EP3 receptorFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001244 Prostaglandin DP receptorFamilyFamily
IPR008365 Prostanoid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink