Entity Details

Primary name HMGB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP30681
EntryNameHMGB2_MOUSE
FullNameHigh mobility group protein B2
TaxID10090
Evidenceevidence at protein level
Length210
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesHmgb2

GO terms

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GOName
GO:0000785 chromatin
GO:0000793 condensed chromosome
GO:0000976 transcription cis-regulatory region binding
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002437 inflammatory response to antigenic stimulus
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0003713 transcription coactivator activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006265 DNA topological change
GO:0006310 DNA recombination
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007283 spermatogenesis
GO:0007289 spermatid nucleus differentiation
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0008584 male gonad development
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0019904 protein domain specific binding
GO:0032075 positive regulation of nuclease activity
GO:0032496 response to lipopolysaccharide
GO:0032728 positive regulation of interferon-beta production
GO:0032991 protein-containing complex
GO:0042056 chemoattractant activity
GO:0043388 positive regulation of DNA binding
GO:0044378 non-sequence-specific DNA binding, bending
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0048545 response to steroid hormone
GO:0050767 regulation of neurogenesis
GO:0050786 RAGE receptor binding
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0060326 cell chemotaxis
GO:0071222 cellular response to lipopolysaccharide
GO:0072091 regulation of stem cell proliferation
GO:0097100 supercoiled DNA binding
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR017967 HMG box A DNA-binding domain, conserved siteSiteConserved site
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions