Entity Details

Primary name DRD3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP30728
EntryNameDRD3_MOUSE
FullNameD(3) dopamine receptor
TaxID10090
Evidenceevidence at transcript level
Length446
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesDrd3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0001975 response to amphetamine
GO:0002016 regulation of blood volume by renin-angiotensin
GO:0002031 G protein-coupled receptor internalization
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006914 autophagy
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007194 negative regulation of adenylate cyclase activity
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007626 locomotory behavior
GO:0008284 positive regulation of cell population proliferation
GO:0008542 visual learning
GO:0014059 regulation of dopamine secretion
GO:0016020 membrane
GO:0019216 regulation of lipid metabolic process
GO:0019904 protein domain specific binding
GO:0030139 endocytic vesicle
GO:0031748 D1 dopamine receptor binding
GO:0032416 negative regulation of sodium:proton antiporter activity
GO:0032467 positive regulation of cytokinesis
GO:0032922 circadian regulation of gene expression
GO:0034776 response to histamine
GO:0035483 gastric emptying
GO:0035815 positive regulation of renal sodium excretion
GO:0040012 regulation of locomotion
GO:0040014 regulation of multicellular organism growth
GO:0042220 response to cocaine
GO:0042493 response to drug
GO:0042995 cell projection
GO:0043066 negative regulation of apoptotic process
GO:0043266 regulation of potassium ion transport
GO:0043278 response to morphine
GO:0045177 apical part of cell
GO:0045187 regulation of circadian sleep/wake cycle, sleep
GO:0045202 synapse
GO:0045471 response to ethanol
GO:0045776 negative regulation of blood pressure
GO:0045840 positive regulation of mitotic nuclear division
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046717 acid secretion
GO:0048148 behavioral response to cocaine
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0050482 arachidonic acid secretion
GO:0050709 negative regulation of protein secretion
GO:0050883 musculoskeletal movement, spinal reflex action
GO:0051481 negative regulation of cytosolic calcium ion concentration
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051580 regulation of neurotransmitter uptake
GO:0051898 negative regulation of protein kinase B signaling
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0060134 prepulse inhibition
GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
GO:0060160 negative regulation of dopamine receptor signaling pathway
GO:0060161 positive regulation of dopamine receptor signaling pathway
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0090325 regulation of locomotion involved in locomotory behavior
GO:0098691 dopaminergic synapse
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099061 integral component of postsynaptic density membrane
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization
GO:1901386 negative regulation of voltage-gated calcium channel activity

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000929 Dopamine receptor familyFamilyFamily
IPR001620 Dopamine D3 receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DRD3_MOUSEPALM_MOUSEBioGRID16386234 details
DRD3_MOUSEPDC6I_MOUSEBioGRID18380665 details